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目的探讨宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)患者宫颈锥形切除术(简称宫颈锥切术)术后妊娠不良结局的相关因素及预防对策。方法随机选择广安市人民医院200例因CIN实施宫颈锥切术患者。对可能影响术后不良妊娠结局的因素进行单因素分析与Logistic回归分析。结果单因素分析共筛选出9个因素与妊娠不良结局有关。经过Logistic回归分析,手术时间长、术中出血量多、妊娠间隔时间短、既往有流产、胎膜早破、早产等非正常生育病史、合并基础疾病等因素为宫颈锥切术后出现不良妊娠结局的相关因素。结论宫颈锥切术后妊娠不良结局是多因素综合作用的结果。术前评估及充分准备,积极治疗患者基础疾病的同时,提高手术技巧,缩短手术时间,术后、孕前给予指导,可减少不良妊娠的发生,对于已受孕的宫颈锥切术后患者应高度重视妊娠期和分娩期的管理。
Objective To investigate the related factors and preventive measures of adverse pregnancy outcome after cervical conization (cervical conization) in patients with cervical intraepithelial neoplasia (CIN). Methods 200 patients were randomly selected from Guang’an People’s Hospital for cervical cone conization. Univariate analysis and logistic regression analysis were used to analyze the factors that may affect the outcome of postoperative adverse pregnancy. Results Univariate analysis of a total of 9 factors were selected and poor outcome of pregnancy related. After Logistic regression analysis, the long operation time, intraoperative blood loss, short gestation interval, the history of abortion, premature rupture of membranes, premature birth and other abnormal birth history, combined with underlying diseases and other factors for cervical conization after adverse pregnancy The outcome of the relevant factors. Conclusions The adverse outcome of pregnancy after conization of the cervix is the result of multifactorial combination. Preoperative assessment and adequate preparation, active treatment of patients with underlying diseases at the same time, improve surgical skills, shorten the operation time, postoperative guidance given before pregnancy, can reduce the incidence of adverse pregnancy, cervical conization has been pregnant patients should pay great attention Gestational and childbirth management.