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近年来,围绕白血病、淋巴瘤的临床研究,先后建立了不少杂交瘤单克隆抗体,其中有些已应用于临床诊断、分类与治疗。单克隆抗体在白血病、淋巴瘤诊断与分类上的研究在白血病、淋巴瘤研究中,由于单克隆抗体的应用,推动了正常白细胞与白血病和淋巴瘤细胞表面标志(抗原)研究工作的进展,这为白血病、淋巴瘤的诊断提供了可靠的依据。有关针对正常白细胞(包括淋巴细胞、粒细胞及单核细胞系)表面分化抗原的的克隆抗体已有不少报导,其中以抗T细胞系的单克隆
In recent years, around the clinical research of leukemia, lymphoma, many hybridoma monoclonal antibodies have been established, some of which have been used in clinical diagnosis, classification and treatment. Monoclonal Antibodies in the Diagnosis and Classification of Leukemias and Lymphomas Research advances in the research of leukocyte and leukemia and lymphoma cell surface markers (antigens) in leukemia and lymphoma research are promoted by the use of monoclonal antibodies For leukemia, lymphoma diagnosis provides a reliable basis. There have been many reports on cloned antibodies against surface-differentiated antigens of normal leukocytes, including lymphocytes, granulocytes and monocyte lines, wherein monoclonal antibodies against T cell lines