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目的:探讨血液灌流(HP)联合连续性静-静脉血液滤过(CVVH)辅助治疗急性重度乌头碱中毒的疗效。方法:将急性重度乌头碱中毒60例患者随机分为对照组和治疗组各30例,对照组给予常规处理,治疗组在对照组的基础上行HP联合CVVH治疗,比较两组的疗效。结果:治疗组平均恶性心律失常复律时间、平均住院时间均明显低于对照组(P<0.01);对照组死亡2例,治疗组均治愈。结论:急性重度乌头碱中毒尽早联合HP和CVVH治疗的疗效确切,可降低死亡率。
Objective: To investigate the therapeutic effect of hemoperfusion (HP) combined with continuous intravenous venous hemofiltration (CVVH) in the treatment of acute severe aconitine poisoning. Methods: 60 patients with acute severe aconitine poisoning were randomly divided into control group and treatment group, 30 cases in each group. The control group was given routine treatment. The treatment group was treated with HP combined with CVVH on the basis of the control group. The curative effect was compared between the two groups. Results: The mean arrhythmia recovery time and average length of hospital stay in the treatment group were significantly lower than those in the control group (P <0.01). Two patients died in the control group and the treatment group were cured. Conclusion: Acute severe aconitine poisoning combined with HP and CVVH early treatment of curative effect is exact, can reduce mortality.