目的解决不接受Miles术式的直肠癌患者进一步有效的治疗问题。方法使用一池多路埋置式动脉导管对20例不接受Miles术式的直肠癌患者行剖腹置管,直肠上、中、下动脉灌注化疗。结果15例4周期化疗,3例6周期化疗,2例12周期化疗,有效率100%。肿瘤不同程度缩小,18例直肠癌肿下缘回缩至距肛门外缘6cm以上,均二期保留肛门切除癌肿。2例癌肿虽有缩小其下缘距肛门仍仅4cm,拒不接受Miles术式,3年后均死于肝转移。结论三动脉灌注化疗能有效延缓直肠癌发展,甚至缩小肿瘤,最终保留肛门根治切除癌肿。一池多路导管使用效果理想。 Objective To solve further treatment problems for patients who do not receive Miles surgery for rectal cancer. Methods Twenty cases of rectal cancer patients who did not receive Miles operation underwent laparotomy, rectal upper, middle and lower arterial infusion chemotherapy using a multi-channel embedding catheter. Results 15 cases of 4 cycles of chemotherapy, 3 cases of 6 cycles of chemotherapy, 2 cases of 12 cycles of chemotherapy, the effective rate of 100%. Tumors reduced to varying degrees, 18 cases of rectal cancer swollen margin retracted to more than 6cm from the anus of the outer margin, both retained anal resection of the cancer. Although two cases of cancer reduced the lower edge of the anus is still only 4cm, refused to accept Miles surgery, died of liver metastases after 3 years. Conclusion Three arterial infusion chemotherapy can effectively delay the development of rectal cancer, and even reduce the tumor, and ultimately retain the anus radical resection of the cancer. A multi-channel catheter with good results.