加拿大Chretien和英国Lowry实验室于1980年先后从人垂体中分离到一种分子量约为12,000的新的醣肽。这种醣肽含76个氨基酸残基,有两个二硫键桥(2、8位及20、24位),在第45位苏氨酸及第65位门冬酰胺上各有一个醣基侧链。目前已经明确,该新发现的醣肽是促肾上腺皮质激素(ACTH)、β-促脂素(β-LPH)、β-内啡肽(β-EP)、(α-和β-促黑素(α- Chretien, Canada and Lowry Laboratory in the United Kingdom in 1980 successively from the human pituitary isolated a molecular weight of about 12,000 new glycopeptide. This glycopeptide contains 76 amino acid residues, two disulfide bridges (2, 8 and 20, 24), one glycosyl at the 45th threonine and the 65th asparagine Side chains. It has now been clear that the newly discovered glycopeptides are ACTH, β-LPH, β-EP, (α- and β-melanoidin (α-