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保肝药物对抗结核药所致的肝功能损害的预防作用临床报告不多。从1990年9月～1992年9月我们应用肝太乐、联苯双脂预防抗结核药的肝损害,临床观察有一定疗效,现报道如下。临床资料一、一般资料 1990年9月至1992年9月住院确诊的初治浸润型肺结核136例,临床能排除肝结核、既往无肝病史,丙氨酸氨基转移酶(ALT)、肝功常规检查均正常,HBsAg(-)。男95例,女41例。年龄76～19岁,平均34.6岁,其中60岁以上者11例。二、观察方法病人的抗结核治疗采用含有异菸肼、利福平的化疗方案,即用HRSZ(HRSE)、HRZ(HRE)。将病例随机分入下列4组,每组各34例。
Preventive effects of hepatoprotective drugs against tuberculosis-induced liver dysfunction are few. From September 1990 to September 1992 we use liver too Le, biphenyl two lipid prevention of anti-TB drugs of liver damage, clinical observation of a certain effect, are reported below. Clinical data First, the general information September 1990 to September 1992 136 cases of newly diagnosed infiltrative pulmonary tuberculosis diagnosed clinically to rule out tuberculosis, no history of previous liver disease, alanine aminotransferase (ALT), liver function All tests were normal, HBsAg (-). 95 males and 41 females. Aged 76 to 19 years old, with an average of 34.6 years old, of which 11 were over 60 years old. Second, the observation method The patient’s anti-TB treatment with chemotherapy containing isoniazid, rifampicin, that is HRSZ (HRSE), HRZ (HRE). The cases were randomly divided into the following 4 groups, 34 cases in each group.