论文部分内容阅读
目的:探讨超声波与冲击波联合负压封闭引流术对儿童血源性骨髓炎炎症的作用。方法:选取2016年9月至2019年10月郑州大学第一附属医院小儿外科收治的符合纳入标准的儿童血源性骨髓炎患者56例，根据采用的治疗方法分为对照组和观察组，每组28例，将采用单纯负压封闭引流术治疗的患者设为对照组，采用超声波与冲击波联合负压封闭引流术治疗的患者设为观察组。比较2组患者入院时与治疗1、2、3周后白细胞计数(WBC)、C反应蛋白(CRP)、降钙素原(PCT)、血沉(ESR)的变化。计数资料用频数或率表示，其差异性比较采用n χ2检验或Fisher精确概率计算法(双侧)。n 结果:入院时，对照组WBC、CRP、PCT、ESR分别为[(15.59±4.2)×10n 9/L、(62.75±40.46) mg/L、(0.45±0.29) μg/L、(56.25±26.78) mm/h]，观察组WBC、CRP、PCT、ESR分别为[(16.23±3.9)×10n 9/L、(67.75±42.75) mg/L、(0.48±0.33) μg/L、(57.45±24.65) mm/h]，两组患者WBC、CRP、PCT、ESR水平比较，差异均无统计学意义(n t＝0.591、0.449、0.361、0.174，P>0.05)。治疗2周后，对照组与观察组ESR分别为(37.13±11.59)、(30.56±10.53) mm/h，差异有统计学意义(n t＝2.220，n P0.05). After 2 weeks of treatment, the ESR in the control group and the observation group was (37.13±11.59) and (30.56±10.53) mm/h, and the difference was statistically significant (n t=2.220, n P<0.05). After 3 weeks of treatment, the WBC in the control group and the observation group were (6.38±2.10)×10n 9/L and (5.37±1.35)×10n 9/L respectively, and the difference was statistically significant (n t=2.220, n P<0.05); the CRP respectively were (4.54±1.18) and (2.03±0.79) mg/L, and there was significant difference between the two groups (n t=9.353, n P<0.05); the PCT respectively was (0.07±0.04) and (0.05±0.03) μg/L, and there was significant difference between the two groups (n t=2.117, n P0.05).n Conclusion:Compared with simple negative pressure closed drainage in the treatment of children with hematogenous osteomyelitis, ultrasound and shock wave combined with negative pressure closed drainage can significantly reduce the inflammatory indexes in children with hematogenous osteomyelitis.