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目的筛选高危人群并早期干预是防治急性肾损伤的重要手段,探讨未参加过训练、训练前未培训、不良心理情绪(紧张、焦虑)、平时体育活动频率少(<3次/周)这4个危险因素能否筛选高强度军事训练致急性肾损伤的高危人群。方法根据问卷调查结果将参加武装越野5 km的战士分为无危险因素组(组1)、1个危险因素组(组2)、2个危险因素组(组3)、3个危险因素组(组4)、4个危险因素组(组5),分别留取训练后6、24 h的尿标本,比较尿蛋白、尿潜血、尿微量白蛋白(m ALB)、N-乙酰-β-D-氨基葡萄糖苷酶(NAG)等肾损伤指标。结果随着危险因素的增加,各组训练后6 h尿蛋白阳性的发生率增加(2=101.8,P<0.001),训练后6 h的m ALB、NAG水平明显升高(F=133.3,P<0.001;F=67.71,P<0.001)。对中高危组(3、4、5组)的分析提示训练后24 h尿m ALB、NAG水平亦随着危险因素增加而增加,以组5的均值最高。结论未参加过训练、训练前未培训、不良心理情绪(紧张、焦虑)、平时体育活动频率少(<3次/周)是发生肾损伤的独立危险因素,可用于筛选高强度军事训练致急性肾损伤高危人群。
Objective To screen high-risk groups and early intervention is an important means of prevention and treatment of acute kidney injury, to explore the lack of training, training before training, psychological distress (stress, anxiety), usually less frequent physical activity (<3 times / week) 4 A risk factor screening of high-intensity military training to acute kidney injury risk groups. Methods According to the results of the questionnaire, soldiers participating in armed off-road 5 km were divided into group without risk factors (group 1), group with 1 risk factors (group 2), group with 2 risk factors (group 3) and group with 3 risk factors Group 4) and 4 groups of risk factors (Group 5). Urine specimens were collected 6 and 24 hours after training respectively. Urinary protein, urine occult blood, urinary albumin (m ALB), N-acetyl-β-D - glucosaminidase (NAG) and other indicators of kidney damage. Results With the increase of risk factors, the urinary protein positive rate increased 6 h after training (2 = 101.8, P <0.001), and the levels of m ALB and NAG at 6 h after training increased significantly (F = 133.3, P <0.001; F = 67.71, P <0.001). Analysis of middle and high risk groups (groups 3, 4, and 5) suggested that urinary ALBAL and NAG levels at 24 hours after training also increased with the increase of risk factors, with the mean of group 5 being the highest. Conclusion No training, no training before training, bad mood and emotion (nervousness and anxiety), usually less frequent physical activity (<3 times / week) is an independent risk factor for renal injury, which can be used to screen high-intensity military training for acute Kidney injury at high risk.