论文部分内容阅读
目的:探讨老年高血压的临床特点及治疗效果。方法:选取2009年6月—2010年6月我院收治的248例老年高血压患者,总结患者的临床特点,将患者分为观察组和对照组两组。观察组患者均口服海捷亚(氯沙坦50mg,氢氯噻嗪12.5mg)1片,每天晨服1次,共4周,对照组患者服用辛伐他汀药物,观察两组患者用该药期间血压、心率及不良反应情况。结果:老年高血压特点以收缩压增高为主,血压波动大,合并症多。口服海捷亚1周起,收缩压、舒张压、平均动脉压均显著下降(P<0.05),至第4周降压幅度最显著(P<0.01),对比辛伐他汀药物效果发生更加快,且不良反应少。结论:老年高血压患者临床特点较为复杂,海捷亚能快速、平稳控制血压,不良反应小。
Objective: To investigate the clinical features and therapeutic effect of senile hypertension. Methods: From June 2009 to June 2010, 248 elderly hypertensive patients admitted to our hospital were selected and their clinical characteristics were summarized. The patients were divided into observation group and control group. Patients in the observation group were orally given 1 tablet of Hypertension (losartan 50mg, hydrochlorothiazide 12.5mg) once a day for 4 weeks. The patients in the control group took simvastatin drugs and observed the blood pressure, Heart rate and adverse reactions. Results: The characteristics of elderly hypertension with systolic blood pressure increased mainly, blood pressure fluctuations, complications. Systolic blood pressure, diastolic blood pressure, and mean arterial pressure were significantly decreased from 1 week after oral administration (P <0.05), with the most significant decrease in the fourth week (P <0.01), and the effect of simvastatin was more rapid , And less adverse reactions. Conclusion: The clinical features of elderly patients with hypertension are more complicated. Haiteya can quickly and smoothly control blood pressure with little adverse reactions.