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目的:探讨微通道钬激光碎石对肾结石患者结石清除率及创伤应激指标的影响。方法:抽取2016年2月至2019年12月于解放军联勤保障部队第九八九医院进行治疗的结石患者100例，按照治疗方法分为对照组(n n＝48)和观察组(n n＝52)。对照组给予标准通道气压弹道联合超声碎石取石治疗，观察组采用微通道钬激光碎石治疗。比较两组患者的围术期相关指标、结石清除率、创伤应激指标及术后并发症发生情况。n 结果:两组患者的住院时间比较差异未见统计学意义(n P>0.05)。观察组手术时间短于对照组[(79.13±9.87)min比(90.36±10.54)min]，术中出血量少于对照组[(78.34±6.89)ml比(89.28±7.32)ml]，止痛药物使用率低于对照组[3.85%(2/52)比20.83%(10/48)]，n P0.05)。术后第1天，两组血清内皮素、C-反应蛋白、白细胞计数等创伤应激指标比较差异未见统计学意义(n P>0.05)；术后1周，两组上述指标均降低，且观察组下降幅度大于对照组，差异有统计学意义(n P0.05); 1 week after operation, the above indexes in the two groups decreased, and the decrease range of the observation group was greater than that of the control group, and the difference was statistically significant (n P<0.05). The incidence of postoperative complications in the observation group (7.69%, 5/52) was significantly lower than that in the control group (22.92%, 11/48),n P<0.05.n Conclusions:Micro-channel holmium laser lithotripsy for treating urinary calculi has characteristics of short operation time, less bleeding, smaller impact on body, high stone clearance rate, fast postoperative recovery and low incidence of complications.