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目的:观察败黄肝宁合剂联合思美泰治疗肝硬化黄疸的临床疗效。方法:将100例肝硬化黄疸患者随机分为两组各50例,对照组采用常规护肝对症支持疗法加思美泰片口服治疗,治疗组在对照组治疗基础上加败黄肝宁合剂口服治疗。观察两组临床疗效及相关生化指标(TBIL、ALT)的变化情况。结果:总有效率治疗组为90.0%,对照组为72.0%,两组比较,差异有统计学意义(P<0.05);两组TBIL、ALT治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:败黄肝宁合剂联合思美泰治疗肝硬化黄疸有较好疗效,较单用思美泰治疗能更好地消退黄疸、促进肝功能恢复。
Objective: To observe the clinical curative effect of defeated HuangGanNing mixture combined with SimeiTai in treating cirrhosis jaundice. Methods: 100 patients with cirrhosis jaundice were randomly divided into two groups of 50 patients. The control group was treated with conventional hepatoprotective supportive therapy plus Gesmeitai tablet. The treatment group was given oral treatment of Huangganning mixture on the basis of the control group treatment. The changes of clinical efficacy and related biochemical indexes (TBIL, ALT) in both groups were observed. Results: The total effective rate was 90.0% in the treatment group and 72.0% in the control group, with significant difference between the two groups (P <0.05). The intra-group comparison of TBIL and ALT before and after treatment and the comparison between the two groups after treatment All were statistically significant (P <0.05). Conclusion: The combination of decoction of Huangganning and Smectite has a good curative effect on jaundice of liver cirrhosis. Compared with the single treatment with Smectite, jaundice can be dissipated better and the recovery of liver function can be promoted.