卵圆孔未闭一般不引起心房间的分流,但近年来发现,卵圆孔的存在与反常性栓塞、脑卒中、偏头痛等疾病的发生相关,因此不可忽视。1卵圆孔未闭的胚胎发育和病理生理改变在胚胎发育至第6、7周,先从原始心房顶部背侧壁,相当于房间沟位置发生一个半月形的褶,即原发隔或称第一隔。此隔 Patent foramen ovale generally does not cause atrial shunt, but in recent years found that the presence of foramen ovale and abnormal embolism, stroke, migraine and other diseases related to, and therefore can not be ignored. A patent foramen ovale embryonic development and pathophysiological changes in the embryo to the first 6,7 weeks, the first from the apex of the roof of the original atrium, the equivalent of a semilunar pleat position of the fold, the primary septum or said The first interval. This interval