Mistakes in interpretation are concerned with not merely poor language competence but also incapability of smooth crosscultural communication,which indicates that interpreters should be more competent in pragmatics consistent to the cultural models of relevance.The analysis demonstrates the importance of understanding cross-cultural pragmatics and some implications for teaching,particularly in the EFL environment.Project-based learning,conforming to the requirements of personnel training against the background of globalization,can well serve the goal of developing students’ overall cross-cultural communication competence in interpretation courses,when culture and its impacts on pragmatic competence of interpretation are not left out in both the in-class and after-class activities,but are dealt with in a sensitive and open-minded way. Mistakes in interpretation with not merely poor language competence but also incapability of smooth crosscultural communication, which indicates that interpreters should be more competent in pragmatics consistent to the cultural models of relevance. The analysis demonstrates the importance of understanding cross-cultural pragmatics and some implications for teaching, particularly in the EFL environment. Project-based learning, conforming to the requirements of personnel training against the background of globalization, can well serve the goal of developing students’ overall cross-cultural communication competence in interpretation courses, when culture and its impacts on pragmatic competence of interpretation are not left out in both the in-class and after-class activities, but are dealt with in a sensitive and open-minded way.