通常把多内分泌缺陷综合征归为两类不同的疾病。第一类大约在12岁以前开始发病。它是以甲状腺机能低下、原发肾上腺机能不足和皮肤粘膜的念珠菌病为特征;也发生脱发、致命性贫血、营养吸收障碍和慢性肝炎。一般把这类疾病称为Ⅰ型多内分泌缺陷综合征。这类疾病的遗传类型常是不清楚 Multiple endocrine-deficient syndromes are usually classified as two different types of disease. The first type begins to occur around the age of 12. It is characterized by hypothyroidism, primary adrenal insufficiency, and mucocutaneous candidiasis; hair loss, fatal anemia, nutritional disorders, and chronic hepatitis also occur. This type of disease is generally referred to as type I polyendocrine deficiency syndrome. The genetic type of such diseases is often unclear