被细胞内病原菌感染的病人在抗生素化疗选择上,吞噬细胞内抗生素的生物活性是一个重要的特性。本文研究了四个新喹诺酮Difloxacin,环丙氟哌酸、甲氟哌酸和Fleroxacin对金葡菌和单核细菌增生利斯特氏菌的吞噬细胞生物活性。体外研究抗菌剂在吞噬细胞内活性,一般是测定其杀菌活性而不是抑菌活性。因此,广泛使用的是菌落计数法。但该法测定抑菌 In patients infected with intracellular pathogens antibiotic chemotherapy options, the biological activity of the phagocytic antibiotics is an important feature. In this paper, the phagocytic activity of four new quinolones Difloxacin, ciprofloxacin, cofloxacin and Fleroxacin on S. aureus and L. monocytogenes was studied. Antibacterial agents in vitro study of phagocytic activity, the general is to determine its bactericidal activity rather than antibacterial activity. Therefore, colony counting is widely used. However, the method of measuring antibacterial