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目的 :探讨水、电解质代谢障碍与高原肺水肿发生的关系 ;方法 :观测高原肺水肿患者治疗前后血、尿电解质对比 ,高原肺水肿患者治疗前与高原同海拔健康人水负荷试验对比 ,从而了解高原肺水肿患者水电解质代谢的变化 ;结果 :显示高原肺水肿患者治疗前后血电解质有轻度的变化 ,但无显著性差异 (P >0 .0 5) ,治疗前后尿电解质有显著性差异 :治疗后尿Na+浓度明显增高 (P <0 .0 1 ) ,K+、Cl- 浓度显著下降 (P <0 .0 5) ,Ca2 +浓度有轻度增高 (P >0 .0 5) ;水负荷试验表明高原肺水肿患者排尿能力在各个时间段及一段时间内明显低于对照组 ;结论 :高原肺水肿患者治疗前存在着水、电解质代谢障碍 ,水、电解质代谢障碍参与了高原肺水肿发生的病理生理过程
Objective: To investigate the relationship between water and electrolytes dysmetabolism and the development of high altitude pulmonary edema. Methods: To compare the blood and urine electrolytes in patients with high altitude pulmonary edema before and after treatment, The results showed that there was a slight change of blood electrolytes in patients with high altitude pulmonary edema before and after treatment, but there was no significant difference (P> 0.05), there was a significant difference in urinary electrolytes before and after treatment: After treatment, urinary Na + concentration increased significantly (P <0.01), K + and Cl- concentrations decreased significantly (P <0.05), Ca2 + concentration increased slightly (P> 0.05) Test showed that patients with high altitude pulmonary edema urination ability in each time period and a period of time was significantly lower than the control group; Conclusion: high altitude pulmonary edema patients before treatment there is water, electrolyte metabolism disorders, water and electrolyte metabolism disorders involved in the high altitude pulmonary edema Pathophysiological process