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绵枣儿来源于风信子科植物绵枣儿Scilla scilloides(Lindl.)Druce的鳞茎。本研究采用HPD100大孔树脂、硅胶、Sephadex LH-20、ODS柱色谱和半制备HPLC等方法,从采自河南信阳的绵枣儿中分离出17个化合物;根据化合物的理化性质和波谱数据,分别鉴定为2-羟基-7-甲氧基绵枣儿素(1),绵枣儿素(2),5,7-dihydroxy-3’,4’-dimethoxyspiro{2H-1-benzopyran-7’-bicyclo[4.2.0]octa[1,3,5]-trien}-4-one(3),socialinone(4),4-甲基白藜芦醇(5),(E)-白藜芦醇(6),scillavone A(7),3,9-dihydroeucomnalin(8),3-(3-羟基-4-甲氧基苄基)-5,7-二羟基苯并二氢吡喃-4-酮(9),(3R)-5,7,3’-trihydroxy-4’-methoxyspiro{2H-1-benzopyran-7’-bicyclo[4,2,0]octa[1,3,5]-trien}-4-one(10),scillabene A(11),2-羟基绵枣儿素(12),3-(4-羟基苄基)-5,7-二羟基苯并二氢吡喃-4-酮(13),3-(4-羟基亚苄基)-5,7-二羟基苯并二氢吡喃-4-酮(14),3-(4-羟基苄基)-5-羟基-7,8-二甲氧基苯并二氢吡喃-4-酮(15),3-(4-羟基苄基)-5-羟基-6,7-二甲氧基苯并二氢吡喃-4-酮(16),3-(4-羟基苄基)-5,8-二羟基-7-甲氧基苯并二氢吡喃-4-酮(17),其中化合物3,4,6,9,13和15~17为首次从绵枣儿植物中分离得到。
Sponge date originated from the bulb of Scilla scilloides (Lindl.) Druce. In this study, 17 compounds were isolated from Scillans datei collected from Xinyang, Henan by HPD100 macroporous resin, silica gel, Sephadex LH-20, ODS column chromatography and semi-preparative HPLC. According to the physicochemical properties and spectral data of the compounds, They were identified as 2-hydroxy-7-methoxy cotton date (1), cotton date (2), 5,7-dihydroxy-3 ’, 4’-dimethoxyspiro { -bicyclo [4.2.0] octa [1,3,5] -trien} -4-one (3), socialinone (4), 4-methyl resveratrol (5), Scillavone A (7), 3,9-dihydroeucomnalin (8), 3- (3-hydroxy-4- methoxybenzyl) -5,7-dihydroxychroman-4 (3R) -5,7,3’-trihydroxy-4’-methoxyspiro {2H-1-benzopyran-7’-bicyclo [4,2,0] octa [1,3,5] - trien} -4-one (10), scillabene A (11), 2- hydroxynil (12), 3- (4- hydroxybenzyl) -5,7-dihydroxychroman- (14), 3- (4-hydroxybenzyl) -5- (4-hydroxybenzyl) -5,7-dihydroxychroman-4- Hydroxy-7,8-dimethoxychromanone (15), 3- (4-hydroxybenzyl) -5-hydroxy-6,7-dimethoxybenzodihydro Pyran-4-one (16), 3- (4-hydroxybenzyl) -5,8-dihydroxy-7-methoxy And-4-one (17), wherein the compound 3,4,6,9,13, and 15 to 17 were isolated from the plant Scilla.