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近几年来发现心血管压力反射敏感性 (BRS)对心肌梗死 (MI)后恶性心律失常和心脏猝死有独立的预测价值 ,反映了自主神经的功能。BRS测定方法很多 ,而Smyth等发明的新福林升压法是被临床广泛应用且证明安全有效的一种。日益增多的证据表明BRS是MI后预测室性心律失常和心源性猝死的良好危险分层指标。近期ATRA MI(automomictoneandreflexesaftermyocardialinfarction)的国际多中心研究证实了这一点。MI后反射性迷走神经张力异常的患者发生室性心律失常和心脏猝死的危险性较高 ,识别这些人群对决定临床治疗有价值。而药物或其他方法对BRS的调节作用也许是减少MI后室性心律失常及心源性猝死的一种新方法。但其保护机制仍在研究中 ,这将可能产生治疗或预防室性心律失常及心脏猝死的新方法。
In recent years, it has been found that cardiovascular stress reflex sensitivity (BRS) has independent predictive value on malignant arrhythmia and sudden cardiac death after myocardial infarction (MI), which reflects the function of autonomic nerve. BRS determination of many ways, and Smyth et al invented the new method of boosting the pressure is clinically widely used and proved a safe and effective. There is growing evidence that BRS is a good risk stratification indicator for predicting ventricular arrhythmias and sudden cardiac death after MI. The recent international multicenter study of ATRA MI (automomictone and reflexes aftermyocardial infection) confirms this. Patients with reflex vagal tone abnormalities after MI are at greater risk for ventricular arrhythmias and sudden cardiac death and identifying these populations is valuable in determining the clinical outcome. Regulatory effect of drugs or other methods on BRS may be a new method to reduce ventricular arrhythmia and sudden cardiac death after MI. However, the mechanism of protection is still under study, which may lead to a new method of treatment or prevention of ventricular arrhythmias and sudden cardiac death.