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２０％的乌拉坦麻醉的大鼠静脉注射ＯＬ－Ｗ（红丝线草醇提水转溶物）分别为ＬＤ５０的１／９０，１／５０、１／３０和１／１０后，平均血压分别下降１５．１％±４．１％、１９．７％±３．８％、２６．８％±７．１％和６７．１％±６．６％，清醒ＳＤ大鼠给予ＯＬ－Ｗ０．８ｇ（生药）７／ｋｇ灌胃后，降压幅度为１．２±０．６ｋＰａ，与给药前相比，Ｐ＜０．０１．在降压机理研究中，ＯＬ－Ｗ脑室给药不引起血压下降，表明ＯＬ－Ｗ的降压部位不在中抠；普萘洛尔、苯海拉明、西米替丁、卡托普利等对其降压作用无明显影响；阿托品可显著减弱其降压作用（Ｐ＜０．０１），提示ＯＬ－Ｗ的降压作用机制可能与Ｍ一受体有关；此外，在整体麻醉开胸猫实验所见，ＴＰｖＲ显著降低，提示其降压机制与直接扩张血管等因素有关。
20% of the urethane anesthetized rats intravenously injected with OL-W (red silk alcohol aqueous extract) were LD50 of 1/90, 1/50, 1/30 and 1/10, the average blood pressure decreased 15.1% ± 4.1%, 19.7% ± 3.8%, 26.8% ± 7.1% and 67.1% ± 6.6% respectively. Awake SD rats were given OL-W 0.8g (Crude drug) 7 / kg after gavage, blood pressure was 1.2 ± 0.6kPa, compared with before administration, P <0.01. In the mechanism of antihypertensive study, OL-W intraventricular administration did not cause blood pressure drop, indicating that the depressurization site of OL-W is not in pulling; propranolol, diphenhydramine, cimetidine, captopril, etc. Atropine significantly reduced its antihypertensive effect (P <0.01), suggesting that the mechanism of OL-W antihypertensive effect may be associated with a M receptor; In addition, the general anesthesia thoracic cat Experimental findings, TPvR significantly reduced, suggesting that its antihypertensive mechanism and direct dilatation of blood vessels and other factors.