17个不同的取代基引入桂皮酰胺的α位,探讨了这些基团对于桂皮酰胺类化合物的抗惊作用的影响。 对化合物的顺反构型作了分析。包括顺式导构体,共合成了20个新化合物。 Seventeen different substituents were introduced into α-position of cinnamic amide, and the effects of these groups on the anti-shock effect of cinnamides were also discussed. The cis-trans configuration of the compounds was analyzed. Including the cis-structure, a total of 20 new compounds were synthesized.