近年来国内外对炎性介质、细胞因子等的深入研究已证实,重症急性胰腺炎(SAP)早期由于机体受到各种物理、化学感染等所致损害的侵袭,引起机体的应激性反应,表现出超强的全身炎症反应综合征,进而造成全身多脏器功能障碍乃至衰竭;稍后期则由于急性肠粘膜损害、肠道细菌易位等导致 In recent years, in-depth studies on inflammatory mediators and cytokines both at home and abroad have confirmed that the severe acute pancreatitis (SAP) caused the body’s stress response by the invasion of the body due to various physical and chemical infections, Showing super systemic inflammatory response syndrome, which led to systemic multiple organ dysfunction and failure; the latter due to acute intestinal mucosal damage, intestinal bacterial translocation and other lead