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目的探讨2型糖尿病患者踝臂指数(ABI)和尿微量白蛋白(MAU)的联系。方法52例2型糖尿病患者分为非PAD组(ABI≥0.9)29例和PAD组(ABI<0.9)23例,分析两组的病程、糖化血红蛋白(HbA1C)、尿素氮(BUN)、肌酐(Scr)、尿微量白蛋白(MAU)等指标。结果PAD组的病程[(32.35±15.50)a]、收缩压[(154±1.08)mmHg]、HbA1[c(8.69±1.08)%]、MAU[(105.13±129.38)mg/L]、BUN[(6.53±1.12)mmol/L]、Sc[r(108.0±21.7)μmol/L]水平均高于非PAD组[(24.21±11.51)a、(140±21)mmHg、(8.03±1.20)%、(44.15±33.72)mg/L、(5.99±0.69)mmol/L、(96.2±18.1)μmol/L],差别有统计学意义(P<0.05);逐步回归分析显示,MAU和BUN是影响ABI的独立因素。结论ABI与MAU和BUN密切相关;伴有MAU的2型糖尿病患者更需要周围血管病变的检测。
Objective To investigate the relationship between ankle brachial index (ABI) and urinary microalbumin (MAU) in type 2 diabetic patients. Methods Totally 52 patients with type 2 diabetes were divided into non-PAD group (ABI ≥0.9), 29 cases and PAD group (ABI <0.9), 23 cases were analyzed. The duration of disease, HbA1C, BUN and creatinine Scr), urine microalbumin (MAU) and other indicators. Results The duration of PAD group was significantly higher than that of PAD group [(32.35 ± 15.50) a], systolic pressure (154 ± 1.08) mmHg, HbA1 [8.69 ± 1.08]%, MAU [105.13 ± 129.38] mg / (6.53 ± 1.12) mmol / L and Sc [r (108.0 ± 21.7) μmol / L) were significantly higher than those in the non-PAD group [(24.21 ± 11.51) (44.15 ± 33.72) mg / L, (5.99 ± 0.69) mmol / L and (96.2 ± 18.1) μmol / L respectively), and the difference was statistically significant (P <0.05) ABI’s independent factors. Conclusion ABI is closely related to MAU and BUN. Patients with type 2 diabetes mellitus with MAU also need to detect peripheral vascular lesions.