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为探明儿童严重脑外伤后血糖水平升高是否与神经病学结局相关,作者回顾复习了16岁以下、GCS≤8的54例脑外伤患儿。结果显示:入院时首次血糖平均为222mg%,其中16例死亡或植物生存者的平均血糖为228mg%;相反,恢复满意或中、重残者38例的平均血糖则为194mg%;提示平均血糖水平随病情进行性恶化而逐渐升高,两者之间显著相关。此外,高血糖还与低血压、酸中毒及早期脑水肿显著相关。虽然脑内血肿或硬膜下血肿均与其预后相关,但本研究仅发现脑内血肿与早期血糖升高相关。颅外损伤与血糖水平无关;白细胞计数作为一种反应应激反应的指标亦与血糖水平显著相关。多变量间的回归分析表明,入院时的GCS 和早期血糖水平对预
To determine if elevated blood glucose levels are associated with neurologic outcomes after a severe traumatic brain injury in children, the authors reviewed 54 children with cerebral trauma under 16 years of age with GCS ≤ 8. The results showed that the average blood glucose at admission was 222mg% on average for the first time, of which 16 were dead or the average blood glucose of plant survivors was 228mg%. On the contrary, the average blood glucose of 38 patients with satisfactory or moderate or severe disability was 194mg% The level gradually increased with the progressive deterioration of the disease, the two were significantly related. In addition, hyperglycemia is also significantly associated with hypotension, acidosis and early brain edema. Although intracerebral hematoma or subdural hematoma are related to their prognosis, this study only found that intracerebral hematoma is associated with an increase in early blood glucose. Extracranial injury has nothing to do with blood glucose levels; white blood cell count as a marker of response to stress is also significantly associated with blood glucose levels. Regression analysis between multivariate variables showed that admission to GCS and early glucose levels were pre-adjusted