湖北省安陆市猪戊型肝炎血清流行病学研究

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目的鉴于湖北省安陆市是猪养殖较为密集区,了解安陆市猪戊型肝炎的感染情况,对湖北省及其周边地区戊型肝炎的防控具有重要的公共卫生学意义。方法 2015年11月-2016年3月,从湖北省安陆市15个乡镇(开发区)共采集174份猪血清样品,其中22个规模猪场,122份血清,25个散养户,52份血清。样品中3月龄以下79份,3月龄以上95份。采用酶联免疫方法对戊型肝炎病毒抗体(HEV-Ab)进行检测。结果 174份猪血清HEV-Ab阳性率为37.9%。规模养殖(38.5%)与散养猪(36.5%)HEV-Ab阳性率差异无统计学意义(χ2=0.061,P=0.805)。阳性规模场占63.6%,阳性散养占40.0%,差异无统计学意义(χ2=2.616,P=0.106)。3月龄以下和3月龄以上猪的HEV-Ab阳性率分别为31.6%和43.2%,两者差异无统计学意义(χ2=2.428,P=0.119)。不同乡镇(开发区)猪HEV-Ab阳性率为0%~90%,差异有统计学意义(χ2=64.779,P=0.000)。结论本地猪群中存在较普遍的HEV感染情况,不同规模、场别、月龄不存在显著差异,不同乡镇(开发区)存在差异。 OBJECTIVE In view of the fact that Anlu City in Hubei Province is a relatively intensive area for pig breeding, understanding the status of swine hepatitis E infection in Anlu has an important public health significance for the prevention and control of hepatitis E in Hubei Province and its surrounding areas. Methods A total of 174 swine serum samples were collected from 15 townships (development zones) in Anlu City, Hubei Province from November 2015 to March 2016. Among them, 22 swine farms, 122 serums, 25 salamanders, 52 Serum. 79 samples below 3 months of age and 95 samples above 3 months of age. The hepatitis E virus antibody (HEV-Ab) was detected by enzyme-linked immunosorbent assay. Results The positive rate of HEV-Ab in 174 pigs was 37.9%. There was no significant difference in the positive rate of HEV-Ab between large-scale farming (38.5%) and free-range pigs (36.5%) (χ2 = 0.061, P = 0.805). The positive size field accounted for 63.6%, positive free-standing accounted for 40.0%, the difference was not statistically significant (χ2 = 2.616, P = 0.106). The positive rates of HEV-Ab in pigs below 3 months and above 3 months were 31.6% and 43.2%, respectively, with no significant difference (χ2 = 2.428, P = 0.119). The positive rate of HEV-Ab in pigs from different towns (development zones) ranged from 0% to 90%, with significant difference (χ2 = 64.779, P = 0.000). Conclusion There are more common cases of HEV infection in the local pig population. There is no significant difference in the scale, field and age of the pigs, and there are differences among different townships (development zones).
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