国际上大量的回顾性研究显示,卡介苗(BCG)是最安全的菌苗之一。目前,每年约有1亿多儿童接受BCG接种。但凡疫苗都存在安全性问题,BCG接种后偶会有一些严重异常反应,如不及时处理,后果严重[1]。本例为BCG接种后出现全身播散性皮肤结核病,经病理证实,给予一、二线抗结核药联合治疗 A large number of international retrospective studies have shown that BCG is one of the safest vaccine. Currently, more than 100 million children receive BCG vaccination each year. Whenever the vaccine has safety issues, there will be some serious abnormalities after BCG inoculation, if not treated in time, the consequences of serious [1]. In this case, systemic disseminated skin tuberculosis occurs after inoculation of BCG. After pathological examination, first- and second-line antituberculosis drugs are given