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应用ＲＴ－ＰＣＲ方法，研究ＨＧＶ感染及复制与ＨＣＣ家庭聚集关系。结果发现，高发家庭成员和低发家庭成员中的ＨＧＶＲＮＡ阳性率分别为３６．４％（２０／５５）和１４．５％（８／５５），经统计学分析有非常显著性差异（Ｐ＜０．０１）。同时还发现肝癌家庭成员中ＨＧＶＲＮＡ也呈家庭聚集现象。提示，ＨＧＶ感染形成的家庭聚集性及复制状态，可能是ＨＣＣ家庭聚集原因之一。ＨＧＶ可能是继ＨＢＶ、ＨＣＶ之后发现的又一种与ＨＣＣ发生关系密切的新型肝炎病毒。
The relationship between HGV infection and replication and HCC family aggregation was studied by RT-PCR. The results showed that the positive rates of HGVRNA in high-risk family members and low-risk family members were 36.4% (20/55) and 14.5% (8/55), respectively. There was a statistically significant difference (P < 0.01). Also found that HGVRNA family members of liver cancer also showed the phenomenon of family aggregation. HGV infection prompted the formation of family aggregation and replication status may be one of the reasons for HCC family aggregation. HGV may be another new type of hepatitis virus that is found after HBV and HCV and has a close relationship with HCC.