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目的：探讨高原缺氧下胸部火器伤邻近心肌组织学和超微结构改变。方法：各选１５只高原杂种犬分为对照组和预防组，致伤后２４ｈ 活杀对照观察。结果：高速投射物致伤后对心肌组织产生较明显的远达效应。对照组病理组织学及超微结构损伤严重，但以心肌细胞本身的超微结构损伤为主。预防组损伤明显减轻，主要表现为心肌间质水肿及毛细血管的组织学改变。结论：上述改变可能与高速投射物致伤时产生的冲击波、血液动力学改变、以及高原缺氧有关，对远离伤道器官损伤应引起临床重视。
Objective: To investigate the changes of myocardial histology and ultrastructure in the vicinity of thoracic firearm injuries under high altitude hypoxia. Methods: Fifteen plateau breeders were divided into control group and prevention group. The control group was killed 24 hours after injury. Results: High-speed projectile produced more obvious effect on myocardial tissue after injury. The histopathological and ultrastructural damage of the control group was serious, but the ultrastructural damage of the myocardial cells was the main one. Prevention of injury significantly reduced group, mainly as myocardial interstitial edema and capillary histological changes. CONCLUSION: The above changes may be related to the shock waves, hemodynamic changes and hypoxia caused by high-speed projectile. It should be paid more attention to the injury of organs far away from the injured wounds.