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应用放射免疫法（ＲＩＡ）测定了５８例急性病毒性肝炎病儿急性期血清三碘甲状腺原氨酸（Ｔ３）、甲状腺素（Ｔ４）和促甲状腺素（ＴＳＨ），并与对照组进行比较。结果表明，５８例中有２０例（３４．４０％）血清Ｔ３低于０．８ｎｍｏｌ／Ｌ，这些病儿血清谷－丙转氨酶均超过６６６８ｎｍｏｌ·ｓ－１／Ｌ；Ｔ４明显增高，与对照组比较差异有极显著意义（Ｐ＜Ｏ．０１），其中３９例（６７．２４％）超过１４５ｎｍｏｌ／Ｌ；ＴＳＨ无明显变化。提示肝炎病儿急性期甲状腺功能可发生改变，主要为高Ｔ４低Ｔ３状态，而且其程度与肝损害的程度有关。临床上对病毒性肝炎病儿血清Ｔ３，Ｔ４进行监测有助于对病情的判断。
Serum triiodothyronine (T3), thyroxine (T4) and thyrotropin (TSH) were measured in 58 children with acute viral hepatitis by radioimmunoassay (RIA), and compared with the control group. The results showed that serum T3 was less than 0.8nmol / L in 20 cases (34.40%) of 58 cases, serum glutamic-pyruvic transaminase was more than 6668nmol · s-1 / L in these cases, T4 was significantly higher than that in control group The difference was significant (P <0.01), of which 39 (67.24%) over 145nmol / L; TSH no significant change. Hypothyroidism in children with acute thyroid function may be changed, mainly for the high T4 low T3 state, and its extent and extent of liver damage. Clinically, the serum of patients with viral hepatitis T3, T4 monitoring will help to determine the condition.