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目的 了解和动态观察广东省实现消除碘缺乏病阶段目标后人群碘营养状况、甲状腺肿和骨密度的变化趋势。方法 用“五方位”抽样法抽查佛冈县5间小学学生共400名进行甲状腺肿、尿碘、盐碘及骨密度调查.骨密度用SD-1000C型单光子骨矿物测定仪测定。结果 8-10岁儿童甲状腺肿大率为6.5%,居民合格碘盐食用率为98.4%,盐碘中位数为29.6 mg/kg,盐碘变异系数为16.7%,尿碘中位数为202.9μg/L;在不同病区间8-10岁儿童骨密度差异无显著性(P>0.05)。8-10岁儿童骨密度分别为0.363g/cm2、0.381/cm2、0.406g/cm2,不同年龄间的骨密度差异有显著性(p<0.001)。结论 2000年实现消除IDD阶段目标及下调加碘盐浓度后,佛冈县的IDD病情是稳定的,呈较为理想的碘营养水平。
Objective To understand and dynamically observe the trend of iodine nutrition, goiter and bone mineral density of population in Guangdong after eliminating iodine deficiency disorders. Methods A total of 400 primary school students in Fogang County were investigated for goiter, urinary iodine, salt iodine and bone mineral density using the “five-spot” sampling method.The bone mineral density was measured by SD-1000C single-photon bone mineral analyzer. Results The prevalence of goiter in children aged 8-10 years was 6.5%. The acceptable iodine salt intake of residents was 98.4%, the median of salt iodine was 29.6 mg / kg, the coefficient of variation of salt iodine was 16.7% and the median of urinary iodine was 202.9 μg / L. There was no significant difference in bone mineral density among children aged 8-10 years (P> 0.05). Bone mineral density of 8-10 year-old children were 0.363g / cm2,0.381 / cm2,0.406g / cm2, bone mineral density difference between different ages was significant (p <0.001). Conclusion IDD stage in Fogang County was stable and showed satisfactory iodine nutrition level after eliminating the target of IDD phase and lowering iodized salt concentration in 2000.