以往研究表明,帕金森病(Parkinson’s disease,PD)的发生是由于黑质多巴胺神经元变性死亡而引起的神经退行性疾病,PD患者以震颤、肌肉僵直、运动迟缓和姿势异常等运动症状为主要临床表现~([1])。PD发病与老龄因素密切相关,流行病学调研显示60岁以上人群发病率可达到1~2%。虽然国内、外学者对于PD进行了大量的基础研究,目前对于导致神经元变性发生的确切机制仍不清楚。近年的研究资料 Previous studies have shown that the occurrence of Parkinson’s disease (PD) is a neurodegenerative disease caused by the degeneration and death of dopaminergic neurons in substantia nigra. PD patients are mainly motile symptoms such as tremor, muscle rigidity, bradykinesia and postural abnormalities Clinical manifestations ~ ([1]). PD incidence and aging factors are closely related to epidemiological studies have shown that the incidence of people over the age of 60 can reach 1 to 2%. Although domestic and foreign scholars have done a lot of basic research on PD, the exact mechanism that causes degeneration of neurons is still unclear. Recent research data