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目的总结重症肢体缺血(CLI)致肌病肾病代谢综合征(MNMS)的诊治经验。方法回顾性分析2005年1月至2008年1月由CLI导致的25例MNMS的临床资料。结果17例存活;2例死于高钾血症引起的心搏骤停,2例死于急性心肌梗死,4例死于以急性肾功能衰竭(ARF)为首发的多器官功能障碍综合征(MODS)。死亡8例,存活17例中保肢15例。结论CLI一旦确诊,应尽早手术。MNMS是CLI的严重并发症,发生静息痛或溃疡时尽快重建血流、肢体坏疽时尽早截肢是预防和治疗MNMS的关键。
Objective To summarize the experience of diagnosis and treatment of metabolic syndrome (MNMS) in myopathic myelopathy due to severe limb ischemia (CLI). Methods The clinical data of 25 cases of MNMS caused by CLI from January 2005 to January 2008 were retrospectively analyzed. Results Seventeen patients survived; two died of hyperkalemia-induced cardiac arrest, two died of acute myocardial infarction and four died of multiple organ dysfunction syndrome (ARF) MODS). 8 died, 15 cases survived limb salvage. Conclusion Once the diagnosis of CLI, surgery should be as soon as possible. MNMS is a serious complication of CLI. It is vital to prevent and treat MNMS as soon as limb amputation extremes as soon as rest pain or ulcer occurs and blood flow is restored.