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目的了解顺义区近3年感染性腹泻的病原菌构成和流行特征。方法收集顺义区2家综合医院肠道门诊2013-2015年947份感染性腹泻患者粪便标本,进行沙门菌、志贺氏菌、副溶血弧菌和致泻性大肠埃希菌(DEC)4种病原菌的检测和分型。结果 947份腹泻患者粪便中检出肠道致病菌183株,检出率为19.32%。其中DEC位居所有检出菌的首位,占44.26%,其次是沙门菌、副溶血弧菌,分别占28.42%和25.68%。DEC以产毒大肠埃希菌(ETEC)为主,沙门菌血清型以肠炎和鼠伤寒沙门菌为主,副溶血弧菌以O3∶K6为主要血清型。结论顺义区感染性腹泻主要病原菌为DEC。
Objective To understand the pathogenic constitution and epidemic characteristics of infectious diarrhea in Shunyi District in recent 3 years. Methods Stool samples from 947 infectious diarrhea patients in two intestine clinics of Shunyi District from 2013 to 2015 were collected and analyzed for four species of Salmonella, Shigella, Vibrio parahaemolyticus and diarrheogenic Escherichia coli (DEC) Pathogenic bacteria detection and typing. Results A total of 183 intestinal pathogens were detected in the urine of 947 diarrhea patients, with a detection rate of 19.32%. Among them, DEC ranked the first place among all detected bacteria, accounting for 44.26%, followed by Salmonella and Vibrio parahaemolyticus, accounting for 28.42% and 25.68% respectively. DEC was mainly produced by E. coli (ETEC). Salmonella serotype was mainly enteritis and Salmonella typhimurium, and Vibrio parahaemolyticus was mainly serotype O3: K6. Conclusions The main pathogen of infectious diarrhea in Shunyi District is DEC.