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甘酮酸100或200mg/kg ip一次,对 Shay 氏法幽门结扎大鼠能抑制溃疡形成,减少胃液的分秘;对阿司匹林诱发的大鼠出血性溃疡有抑制作用。甘酮酸100或200mg/kg po 10次,能抑制醋酸诱发的大鼠慢性溃疡,其抗溃疡作用与日本已上市的 FM100(Aspalon)相似。
100mg / kg or 100mg / kg ip once, pyloric ligation of Shay’s pylorus rats can inhibit the formation of ulcers, reduce gastric secretions; Aspirin-induced hemorrhagic ulcer inhibition. Ketoacid 100 or 200mg / kg po 10 times, can inhibit acetic acid-induced chronic ulcer in rats, its anti-ulcer effect and Japan has been listed FM100 (Aspalon) similar.