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作者报道在德国进行的 Lederle/Take-da百日咳无细胞菌苗DTP(APDT)免疫接种婴儿的现场试验结果,并与Lederle百日咳全细胞菌苗DTP进行免疫原性和反应原性的比较.试验采用双百法,选择149名3～5月龄健康婴儿,其中75名接受APDT,74名接受DTP.每次肌肉注射0.5ml,间隔6～8周,共注射3次.密切注意注射后72小时的局部和全身反应,并观察注射后2星期内有无呼吸道和其他疾病的发生.免疫前和第3次注射
The authors report the field test results of a Lederle / Take-da pertussis acellular vaccine DTP (APDT) vaccinated infants in Germany and immunogenicity and reactivity with Lederle pertussis whole cell vaccine DTP.Experiment uses Double-hundred law, select 149 3 to 5 months old healthy infants, 75 of them received APDT, 74 received DTP.Each intramuscular injection of 0.5ml, an interval of 6 to 8 weeks, a total of 3 injections. Pay close attention to 72 hours after injection Of the local and systemic reactions, and observe the presence of respiratory and other diseases within 2 weeks after injection .Pre-immunization and the third injection