论文部分内容阅读
随着人们对医学遗传学知识的不断增加,依据发病率和死亡率提供遗传病的频率和财政负担是很重要的。近来,发达国家的几项研究表明,遗传病是儿科和医疗机构住院及死亡的主要原因。据作者所知,到目前为止在拉丁美洲其它国家只有两份调查,一份是Berreiro等对在阿根廷布宜若斯艾利斯省立儿童医院的调查,他发现25％的病人是因遗传病或先天缺陷入院;另一份是在委内瑞拉首都加拉加斯,其出生缺陷占儿科住院病人的10％。在墨西哥,Armendares等对两所儿科医院的研究表明,约有6％的病人死于遗传原因,有遗传因素的疾病占20％。本文对在墨西哥国立儿科学研究所儿科住院病人,从遗传学确定疾病的频率和经济负担的全部资料进行了研究。材料和方法国立儿科学研究所是一座具有350张床位的综合性儿科医院,主要提供三级医疗及临床教学,同时也是一座研究中心。主要为墨西哥全国各地和墨西哥城的儿童提供服务
With the increasing knowledge of medical genetics, it is important to provide the frequency and financial burden of genetic diseases based on morbidity and mortality. Recently, several studies in developed countries have shown that genetic diseases are the major cause of hospitalization and death in pediatric and medical institutions. According to the author’s knowledge, only two surveys have been conducted in other countries in Latin America so far. One is Berreiro et al.’s survey of the Children’s Hospital of Ellis Provincial Hospital in Buenos Aires, Argentina. He found that 25% of the patients are due to hereditary diseases. Or congenital defects admitted to the hospital; the other is in Caracas, the capital of Venezuela, whose birth defects accounted for 10% of pediatric inpatients. In Mexico, Armendares et al.’s study of two pediatric hospitals showed that about 6% of patients died of genetic causes, and 20% of diseases had genetic factors. This article examines all the data on the frequency and economic burden of determining the disease in the pediatric inpatients at the Mexican National Institute of Pediatrics. Materials and Methods The National Institute of Pediatrics is a 350-bed comprehensive pediatric hospital that provides tertiary medical and clinical teaching as well as a research center. Mainly serves children from all over Mexico and Mexico City