鼻息肉是多种因素作用下的鼻粘膜慢性炎性病变。其中 ,以病变组织中嗜酸性粒细胞浸润增多为病理特征的鼻息肉约占 80 %～ 90 % ,其发生机制尚未阐明。局部微环境中组织来源的细胞因子 ,对包括嗜酸性粒细胞在内的炎性细胞的生物学活性发挥重要的调控作用。在目前缺乏统一的宏观 Nasal polyps are a variety of factors under the chronic inflammatory lesions of the nasal mucosa. Among them, the pathological changes of eosinophils in pathological features of nasal polyps account for about 80% to 90%, the mechanism has not yet been elucidated. Tissue-derived cytokines in the local microenvironment play an important regulatory role in the biological activity of inflammatory cells, including eosinophils. In the current lack of a unified macro