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临床分子流行病学资料提示 ,肿瘤抑制基因p5 3 72密码子的单核苷酸多态性 (singlenucleotidepolymorphism ,SNP)与某些与人类乳头瘤病毒 (humanpapillomavirus,HPV)感染有关的肿瘤密切相关[1,2 ] ;这一多态性还可能增加丙型肝炎病毒(hepatitisCvirus,HCV)某些亚型感染的易感性[
Clinical molecular epidemiological data suggest that the single nucleotide polymorphism (SNP) of the p3537 codon of the tumor suppressor gene is closely related to some tumors associated with human papillomavirus (HPV) infection [1 , 2]. This polymorphism may also increase the susceptibility of some subtypes of hepatitis C virus (HCV) infection [