论文部分内容阅读
目的:探讨不同年龄及前列腺特异性抗原(PSA)分组对12针穿刺活检前列腺癌检出率及肿瘤特征的影响。方法:临床表现怀疑前列腺癌患者210例,按照患者的年龄分为≤59岁组、60～69岁组、70～79岁组、≥80岁组,按照PSA水平分为0～4μg/L组、4.1～10μg/L组、10.1～20μg/L组、20.1～50μg/L组、>50μg/L组,记录患者临床资料及活检结果。提出不同的穿刺方案并计算其检出率。结果:210例怀疑为前列腺癌患者,检出前列腺癌91例,总的前列腺癌检出率为43.3%,随着年龄的增长,PSA水平的提高,检出率逐渐提高。年龄的增长、PSA水平的提高与体积较大、分级较高的肿瘤密切相关。外周带穿刺与旁正中矢状尖部穿刺有较高的前列腺癌检出率。当患者年龄<60岁,PSA水平<20μg/L时,12针穿刺活检为较佳方案。结论:12针穿刺活检可以弥补6针穿刺活检的缺陷,随着患者年龄的增长,PSA水平的提高,肿瘤的体积增大、病理分级较差。传统6针穿刺法与12针相比,受患者年龄、PSA水平的影响较大。
Objective: To investigate the different age and prostate specific antigen (PSA) group of 12-pin biopsy of prostate cancer detection rate and tumor characteristics. Methods: A total of 210 patients with suspected prostate cancer were enrolled in this study. According to the age of the patients, they were divided into groups of ≤59 years old, 60-69 years old, 70-79 years old, and ≥80 years old. According to PSA level, they were divided into 0-4μg / L group , 4.1 ~ 10μg / L group, 10.1 ~ 20μg / L group, 20.1 ~ 50μg / L group and> 50μg / L group. The clinical data and biopsy results were recorded. Proposed different puncture program and calculate the detection rate. Results: Among the 210 suspected prostate cancer patients, 91 cases of prostate cancer were detected, and the total detection rate of prostate cancer was 43.3%. As the age increased, the PSA level increased and the detection rate gradually increased. Increasing age is associated with an increase in PSA level associated with a larger, higher-grade tumor. Peripheral zone puncture and paracentesis puncture have a higher detection rate of prostate cancer. When the patient is under 60 years of age and the PSA level is <20 μg / L, a 12-gauge needle biopsy is the preferred protocol. Conclusion: The 12-needle biopsy can make up for the defect of 6-needle biopsy. As the patient’s age increases, the PSA level increases, the volume of the tumor increases, and the pathological grade is poor. Traditional 6-needle puncture method compared with the 12-pin, subject to the patient’s age, PSA level greater impact.