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小儿急性多颗粒早幼粒细胞白血病(APL)是小儿白血病中较难治的一种,预后较差,三年存活率为15～35%,国外进行骨髓移植可显著改善预后,长期存活率可达45～70%,但供髓来源较困难,因此,我们开展了胎肝移植治疗本病,现报告1例胎肝移植后已无病存活二年的病例,并讨论有关问题。病历摘要男孩,12岁2月,于84年2月15日因发热,白细胞减低1个月入院。诊断:APL。诱导缓解:HOP 方案×6疗程,HOMP×2。巩固治疗 COMP×2。预防脑白:CR 后 M-
Children acute multi-particle promyelocytic leukemia (APL) is a more refractory childhood leukemia, the prognosis is poor, three-year survival rate of 15 to 35%, foreign bone marrow transplantation can significantly improve the prognosis, long-term survival rate Up to 45 ~ 70%, but it is more difficult to supply the marrow. Therefore, we conducted fetal liver transplantation for the treatment of this disease. We report the case of one case of disease-free survival after two years of fetal liver transplantation and discuss the related issues. Medical summary boy, 12 years old in February, February 15, 84 due to fever, leukopenia 1 month admission. Diagnosis: APL. Induction of remission: HOP program × 6 courses, HOMP × 2. Consolidation treatment COMP × 2. Prevention of brain white: CR after M-