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去年,笔者曾有机会去欧洲等有关国家考察访问。在考察中发现,这些年来欧美学者对病毒性肝炎的抗病毒疗法有不少新的资料。本文就目前有关干扰素、阿糖腺苷和无环鸟苷等抗病毒疗法的近况简述如下。一、干扰素(1FN)根据欧美和日本的经验,α-干扰素对乙型肝炎病毒有肯定的抑制作用。每日肌注2.5～5.0×10~6U/m~2或隔日注射两倍量,3～6个月后,约26～67%慢性乙型肝炎患者的 HBV DNA/DNAP 持续转阴或明显降低、HBeAg 转阴和抗-HBe 阳转,但 HBsAg
Last year, I had the opportunity to visit other countries in Europe. During the investigation, it was found that there have been many new data on anti-virus therapy of viral hepatitis in Europe and the United States in recent years. In this paper, the current status of antiretroviral therapy such as interferon, vidadenosine and acyclovir is summarized as follows. First, interferon (1FN) According to Europe and the United States and Japan’s experience, α-interferon has a positive effect on hepatitis B virus inhibition. Daily intramuscular injection of 2.5 ~ 5.0 × 10 ~ 6U / m ~ 2 or twice daily injection, after 3 ~ 6 months, about 26 ~ 67% of patients with chronic hepatitis B, HBV DNA / DNAP continued negative or significantly reduced , HBeAg negative and anti-HBe positive, but HBsAg