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目的：探讨法莫替丁与泮托拉唑治疗小儿消化性溃疡的临床疗效和经济效益学比较。方法：本研究选取了2012年4月至2013年4月我院收治的126例消化性溃疡患儿作为研究对象，将126例患儿随机分为对照组和观察组，每组各63例，对照组患儿采用泮托拉唑治疗，观察组患儿采用法莫替丁治疗，对比两组患儿的临床疗效及治疗花费情况。结果：对照组患儿的治疗总有效率为95.2%；观察组患儿的治疗总有效率为93.7%，两组患儿的治疗总有效率无明显差异（p>0.05）。观察组组患儿的成本-效果比较对照组明显降低（p<0.05）。观察组患儿的治疗费用较对照组明显减少（p<0.05）。结论：法莫替丁治疗小儿消化性溃疡的效果好，治疗花费少，经济效益，值得推荐。
Objective: To investigate the clinical efficacy and economic benefit of famotidine and pantoprazole in children with peptic ulcer. Methods: A total of 126 children with peptic ulcer admitted to our hospital from April 2012 to April 2013 were enrolled in this study. 126 children were randomly divided into control group and observation group, with 63 cases in each group. The control group of children treated with pantoprazole, the observation group of children treated with famotidine, compared two groups of children’s clinical efficacy and treatment costs. Results: The total effective rate was 95.2% in the control group. The total effective rate in the observation group was 93.7%. There was no significant difference in the total effective rate between the two groups (p> 0.05). The cost-effectiveness of the observation group was significantly lower in the control group (p & lt; 0.05). Treatment costs in the observation group were significantly lower than those in the control group (p & lt; 0.05). Conclusion: Famotidine in children with peptic ulcer effect, treatment less cost, economic benefits, it is recommended.