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目的探讨急性冠脉综合征(ACS)患者血清脂蛋白(a)[LP(a)]及肌钙蛋白I(cTnI)检测的临床意义。方法收集110例ACS患者,包括急性心肌梗死(AMI组)60例,不稳定型心绞痛(UA组)50例,测量治疗前血清LP(a)、cTnI浓度。另取50例稳定型心绞痛患者为对照组,对检测结果进行统计学分析。结果 ACS组LP(a)、cTnI水平均显著高于对照组(P<0.05),AMI组血清cTnI显著高于UA组(P<0.05)。结论血清LP(a)、cTnI联合检测对急性冠脉综合征的诊断和危险度分层具有重要临床意义。
Objective To investigate the clinical significance of serum lipoprotein (a) [LP (a)] and troponin I (cTnI) in patients with acute coronary syndrome (ACS). Methods A total of 110 patients with ACS were enrolled, including 60 AMI patients and 50 patients with unstable angina pectoris (UA group). Serum LP (a) and cTnI concentrations were measured before treatment. Another 50 patients with stable angina pectoris as control group, the test results were statistically analyzed. Results The levels of LP (a) and cTnI in ACS group were significantly higher than those in control group (P <0.05). The serum cTnI in AMI group was significantly higher than that in UA group (P <0.05). Conclusion Serum LP (a), cTnI combined detection of acute coronary syndrome diagnosis and risk stratification has important clinical significance.