作者首次报导父、子二人均患肺动脉闭锁伴发室间隔缺损,这说明复杂型先天性心脏病有遗传基础,提出对致命性心脏畸形幸存者,进行遗传咨询的重要性。近年来对较小年龄的复杂紫绀型先天性心脏病,能够成功地进行矫治手术,因此这些病人的子代。发生心血管畸形的数字应引起人们的关注。 The authors first report that both the father and the son suffer from pulmonary atresia with ventricular septal defect, indicating that the genetic basis of complex congenital heart disease, put forward the importance of genetic counseling for survivors of fatal cardiac malformations. In recent years, the younger age of complex cyanotic congenital heart disease, can be successfully carried out orthodontic surgery, and therefore the offspring of these patients. The number of cardiovascular malformations should cause people’s attention.