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目的 :探讨持续性静脉血液透析滤过在治疗流行性出血热并发急性呼吸衰竭中的临床价值。方法 :对 10例流行性出血热并发急性呼吸衰竭患者行持续静 静脉血液透析滤过 ,每次持续 12h ,同时观察治疗前后血尿素氮、肌酐的变化及监测动脉血氧饱和度、氧合指数 (PaO2 /FiO2 )、呼吸频率、中心静脉压、平均动脉压、心率。结果 :肌酐、尿素氮、中心静脉压下降 (P <0 .0 0 1) ,氧饱和度、氧合指数有所改善 (P <0 .0 0 1) ,呼吸频率、平均动脉压和心率有所下降 ,但差异无显著性 (P >0 .0 5 )。结论 :持续性静 静脉血液透析滤过是流行性出血热并发急性呼吸衰竭的一种有效治疗方法。
Objective: To investigate the clinical value of continuous venous hemodiafiltration in the treatment of epidemic hemorrhagic fever complicated with acute respiratory failure. Methods: Ten patients with epidemic hemorrhagic fever complicated with acute respiratory failure were treated with continuous venous hemodiafiltration, each lasting 12 hours. At the same time, the changes of blood urea nitrogen, creatinine and arterial oxygen saturation, oxygenation index (PaO2 / FiO2), respiratory rate, central venous pressure, mean arterial pressure, heart rate. Results: Creatinine, blood urea nitrogen and central venous pressure decreased (P <0.01), oxygen saturation and oxygenation index improved (P <0.01), respiratory rate, mean arterial pressure and heart rate But there was no significant difference (P> 0.05). Conclusion: Continuous venous hemodiafiltration is an effective treatment for patients with epidemic hemorrhagic fever complicated by acute respiratory failure.