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10种中药有效成分在体外对钙离子载体A_(23187)刺激人多形核白细胞产生白三烯B_4影响试验的结果表明:1×10~(-5)mol/L的大黄素的抑制率为100%,3×10~(-5)mol/L齐墩果酸的抑制率为45.5±4.4%,1×10~(-4)mol/L的放线瑞香宁、去氧胆酸等也有一定抑制作用。
The effect of 10 active ingredients of Chinese herbs on the production of leukotriene B_4 stimulated by human calcium polymorphonuclear leukocytes by calcium ionophore A_(23187) in vitro showed that the inhibitory rate of 1×10 -5 mol/L emodin The inhibition rate of 100%, 3×10 -5 mol/L oleanolic acid was 45.5±4.4%, and 1×10 -4 mol/L of actinomycin, deoxycholic acid, etc. Certain inhibition effect.