This paper introduces and analyzes a detection scheme for adaptive suppressionof Multiuser Access Interference (MAI) and MultiPath Distortion (MPD) for mobile station ofDS/CDMA system. The proposed detection scheme may amount to a RAKE receiver structure,wherein each branch is considered as a linear multiuser filter designed under a Linear ConstrainedMinimum Variance (LCMV) optimization strategy to suppress MAI, followed by a proper combin- This paper introduces and analyzes a detection scheme for adaptive suppression of Multiuser Access Interference (MAI) and MultiPath Distortion (MPD) for mobile station of DS / CDMA system. The proposed detection scheme may amount to a RAKE receiver structure, where each branch is considered as a linear multiuser filter designed under a Linear Constrained Minimum Variance (LCMV) optimization strategy to suppress MAI, followed by a proper combin-