嗜碱性粒细胞在白细胞分类中虽然只占很小的比例,但在变态反应中发挥着重要的作用。它通过其表面FcRIs受体的激活而介导变态反应。本研究比较了16名健康志愿者和12例哮喘患者嗜碱性粒细胞在IgE结合试验前后细胞因子及化学因子的释放情况,并且与组胺释放及皮肤点刺试验结合起来。健康对照及哮 Although basophils account for only a small percentage of leucocyte subsets, basophils play an important role in allergic reactions. It mediates allergy through the activation of its surface FcRIs receptors. This study compared the release of cytokines and chemokines from basophils in 16 healthy volunteers and 12 asthmatics before and after IgE binding assays and was combined with histamine release and skin prick tests. Healthy control and asthma