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目的探讨小儿腹泻患者大便培养结果与心肌损伤标志物水平的关系。方法收集2012年9月-2016年9月在本院就诊的腹泻患儿650例,进行粪便培养,检测患儿血清中心肌损伤标志物肌钙蛋白I(c Tn I)和肌红蛋白(Mb)、肌酸肌酶同工酶(CK-MB),探讨大便培养结果与心肌损伤标志物水平的关系。结果腹泻组患儿CK-MB正常320例、异常330例,Mb正常380例、异常270例,c Tn I正常327例、异常323例,与对照组比较,异常率明显升高,差异有统计学意义(P<0.05)。轮状病毒腹泻组患儿CK-MB正常59例、异常191例,Mb正常100例、异常150例,c Tn I正常72例、异常178例,与细菌阳性组和阴性组对比,异常率均升高,差异有统计学意义(P<0.05)。结论轮状病毒腹泻患儿血清中心肌损伤标志物明显异常,而且患儿电解质紊乱情况更明显,值得临床重点关注。
Objective To investigate the relationship between the results of stool culture and the level of myocardial injury markers in children with diarrhea. Methods A total of 650 children with diarrhea admitted to our hospital from September 2012 to September 2016 were collected for stool culture and cTnI and Mb ), Creatine kinase isoenzyme (CK-MB) to explore the relationship between stool culture and myocardial injury markers. Results There were 320 cases of normal CK-MB in children with diarrhea, 330 cases of abnormality, 380 cases of normal Mb, 270 cases of abnormality, 327 cases of normal c Tn I and 323 cases of abnormality. Compared with the control group, the abnormal rate was significantly increased Significance (P <0.05). In the rotavirus diarrhea group, 59 cases were normal CK-MB, 191 cases were abnormal, 100 cases were normal Mb, 150 cases were abnormal, 72 cases were normal cTn I and 178 cases were abnormal. Compared with the positive and negative bacterial groups, Increased, the difference was statistically significant (P <0.05). Conclusion Serum markers of myocardial damage in children with rotavirus diarrhea were significantly abnormal, and electrolyte imbalance in children was more obvious, which deserved clinical attention.