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目的探讨分析左旋甲状腺素对老年亚临床甲减患者血脂代谢的影响。方法选取我院2013年9月-2014年9月收治入院的50例老年亚临床甲减患者,给予左旋甲状腺素治疗后,分析血脂代谢变化及特点。结果经治疗后患者的TC和LDL水平明显低于治疗前,差异具有统计学意义(P<0.05)。而治疗前、后TG与HDL水平无明显变化,差异无统计学意义(P>0.05)。结论老年亚临床甲减患者经左旋甲状腺素治疗后可明显改善异常的血脂代谢,降低心血管疾病发生的风险。
Objective To investigate the effect of levothyroxine on blood lipid metabolism in elderly patients with subclinical hypothyroidism. Methods Fifty elderly patients with subclinical hypothyroidism admitted to our hospital from September 2013 to September 2014 were enrolled in this study. After levothyroxine treatment, the changes of lipids metabolism and their characteristics were analyzed. Results After treatment, the levels of TC and LDL in patients were significantly lower than those before treatment, the difference was statistically significant (P <0.05). However, there was no significant difference between the levels of TG and HDL before and after treatment (P> 0.05). Conclusion The elderly patients with subclinical hypothyroidism after levothyroxine treatment can significantly improve abnormal lipid metabolism, reduce the risk of cardiovascular disease.