制造脊髓灰质炎疫苗时,常有必要测定感染细胞培养液中的病毒数量。理论上其滴度不应随测定方法和指示细胞的不同而改变,但实际上不同方法结果不尽一致。为此,作者用猴肾细胞和Vero细胞作指示细胞,比较了脊髓灰质炎病毒(Ⅰ、Ⅱ、和Ⅲ型)的三种 When producing polio vaccines, it is often necessary to determine the amount of virus in the infected cell culture. In theory, its titer should not change with the determination of the method and the indicator cells, but in fact the results of different methods are not the same. For this reason, the authors used monkey kidney cells and Vero cells as the indicator cells and compared three types of poliovirus (type I, II, and III)